EL0853 |
MALAT1 |
proliferative vitreoretinopathy |
Microarray, qRT-PCR |
biofluid of PVR (Proliferative VitreoRetinopathy) patients |
up-regulated |
expression |
MALAT1 was significantly up-regulated in the cellular and plasma fraction of peripheral blood in PVR patients. In vitro experiments revealed the role of MALAT1 in regulating RPE proliferation and migration, which is critical for ERMs formation. MALAT1 is a potential prognostic indicator and a target for the diagnosis and gene therapy for PVR diseases. |
26241674 |
|