Related LncRNAs
ID	lncRNA Name	Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
EL0556	H19	pre-eclampsia	N/A	N/A	N/A	mutation	LOI of H19 can be identified in pre-eclamptic placentas and is associated with maternal blood pressures, which implies the involvement of H19 gene LOI in the pathogenesis of pre-eclampsia and its potential relationship with the severity of the disease.	19570415	LncRNADisease
EL0578	HOTAIR	pre-eclampsia	qRT-PCR, knockdown, overexpression	placentas from pre-eclampsia (PE) pregnant women	up-regulated	expression	HOTAIR is probably involved in the onset of preeclampsia by regulating proliferation, invasion and apoptosis of trophoblast cells.	25807808
EL0853	MALAT1	pre-eclampsia	short interfering RNA (siRNA)	placentas from the patients with preeclampsia, EG-3 trophoblast cell line	down-regulated	interaction	Silencing of MALAT-1 in JEG-3 cells suppressed proliferation and induced cell cycle arrest at G0/G1 phase. The migration rate and the invasiveness of JEG-3 cells were suppressed when MALAT-1 was downregulated. MALAT-1 may play an important role in the regulation of proliferation, cell cycle, apoptosis, migration and invasion of trophoblast cells, and under-expression of MALAT-1 during early placentation may be involved in the pathogenesis of preeclampsia.	26722461