| Related LncRNAs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source |
| EL0033 | Adapt15 | obesity | knockdown | mutant Chinese hamster ovary cell line | N/A | mutation | Here we report that gadd7 is induced by lipotoxic stress in a reactive oxygen species (ROS)-dependent fashion and is necessary for both lipid- and general oxidative stress-mediated cell death. Depletion of gadd7 by mutagenesis or short hairpin RNA knockdown significantly reduces lipid and non-lipid induced ROS | 19150982 | |
| EL0239 | BDNF-AS | obesity | N/A | N/A | N/A | mutation | Association identified by GWAS (rs4074134, A118887G). | 19079260 | LncRNADisease |
| EL0239 | BDNF-AS | obesity | N/A | N/A | N/A | locus | This locus maps near key hypothalamic regulators of energy balance, may be associated with obesity. | 20935630 | LncRNADisease |
| EL0320 | CYP2C91 | obesity | Weighted Gene Co-expression Network Analysis (WGCNA) | N/A | N/A | expression | In the current exploratory analysis, we show how a lncRNA - cyp2c91 contributes to the transcriptional regulation localized to cytoplasm thereby making refractory environment for transcription. | 26284111 | |
| EL0556 | H19 | obesity | N/A | N/A | N/A | epigenetics | Insulin-like Growth Factor 2/H19 Methylation at Birth and Risk of Overweight and Obesity in Children. | 22341586 | LncRNADisease |
| EL0973 | NEAT1 | obesity | reexpression | adipocyte-derived stem cells (ADSCs) isolated from wild-type and microRNA 140 (miR-140) knockout mice | N/A | expression | MiR-140 knockout ADSCs have dramatically decreased adipogenic capabilities associated with downregulation of NEAT1 expression. Reexpression of NEAT1 in miR-140 knockout ADSCs is sufficient to restore their ability to undergo differentiation. | 26457124 | |
| EL1222 | SNHG11 | obesity | N/A | N/A | N/A | mutation | New gene associated with obesity. | 20532202 | LncRNADisease |