Related LncRNAs |
ID |
lncRNA Name |
Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
EL0289 |
CDKN2B-AS1 |
myocardial infarction |
N/A |
N/A |
N/A |
mutation |
Association identified by GWAS. |
17478679 |
LncRNADisease
|
EL0289 |
CDKN2B-AS1 |
myocardial infarction |
N/A |
N/A |
N/A |
mutation |
association identified by GWAS (rs4977574, A>G). |
19198609 |
LncRNADisease
|
EL0869 |
MIAT |
myocardial infarction |
N/A |
N/A |
N/A |
mutation |
In vitro functional analyses revealed that the minor variant of one SNP in exon 5 increased transcriptional level of MIAT. Moreover, unidentified nuclear protein(s) bound more intensely to risk allele than non-risk allele. These results indicate that the altered expression of MIAT by the SNP may play some role in the pathogenesis of MI. |
17066261 |
LncRNADisease
|
EL0869 |
MIAT |
myocardial infarction |
N/A |
N/A |
N/A |
mutation |
SNPs associated with myocardial infarction localized to a haplotype block that encompassed the last 3 exons of MIAT. |
20951849 |
LncRNADisease
|
EL0869 |
MIAT |
myocardial infarction |
N/A |
N/A |
N/A |
mutation |
MIAT lincRNA Variants Confer Susceptibility to Myocardial Infarction |
23104877 |
LncRNADisease
|
EL0869 |
MIAT |
myocardial infarction |
N/A |
N/A |
N/A |
regulation |
A myocardial infarction-associated transcript (MIAT), also known as RNCR2 or Gomafu, is a long intergenic non-coding RNA that presents many genetic variants implicated in different processes. A large scale case-control association study regarding cardiovascular disease demonstrates that a MIAT variant (rs2301523) confers susceptibility to myocardial infarction. |
24113581 |
LncRNADisease
|
|