EL0950 |
MVIH |
microvascular invasion in hepatocellular carcinoma |
real-time polymerase chain reaction (PCR), Luciferase reporter assay and RNA immunoprecipitation experiment |
tumor tissue of HCC patients and in HCC cells, including SMMC7721 and HepG2 cells. |
up-regulated |
expression |
Si-MVIH inhibited HCC cell viability and promoted cell apoptosis, but this effect was reversed by miR-199a inhibitor. In nude mice with transplantation, the tumor volume was reduced by si-MVIH, and miR-199a inhibitor canceled this decrease. |
26347410 |
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