| Related LncRNAs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ID | lncRNA Name | Disease | Method | Sample | Expression pattern | Dysfunction type | Description | PMID | Source |
| EL0556 | H19 | meningioma | N/A | N/A | N/A | epigenetics | An examination of meningiomas (World Health Organization grades I-III) demonstrated more robustly that the imprinting status of H19 is perturbed with LOI in a significant number of these tumors. | 20380817 | LncRNADisease |
| EL0556 | H19 | meningioma | N/A | N/A | N/A | regulation | Epigenetic deregulation of lncRNAs genes is associated with disease | 23791884 | LncRNADisease |
| EL0556 | H19 | meningioma | qPCR etc. | meningioma tissue | differential expression | N/A | In total, 24 meningiomas of WHO grade I, II and III were analysed. 15 meningiomas (63%) were informative for the ApaI polymorphism in the IGF2 gene. Monoallelic expression (MAE) for IGF2 was found in 11 out of 15 tumours (73%) which is in contrast to the lack of imprinting status of IGF2 in leptomeninges. Ten cases (42%) were heterozygous for the H19 gene and biallelic expression was found in 3 out of 10 meningiomas (30%). These results indicate that modulation of the imprinting status of IGF2 and H19 may play an important role for the development of meningiomas. | 10738131 | Lnc2Cancer |
| EL0861 | MEG3 | meningioma | N/A | N/A | N/A | regulation | MEG3: a novel long noncoding potentially tumour-suppressing RNA in meningiomas. | 23307326 | LncRNADisease |
| EL0861 | MEG3 | meningioma | qPCR, Luciferase reporter assay, ISH etc. | meningioma tissue | down-regulated | epigenetics | Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. | 20179190 | LncRNADisease Lnc2Cancer |
| EL0986 | NOS2 | meningioma | qPCR etc. | meningioma tissue | up-regulated | expression | anti-NOS2A is a lncRNA that is expressed in meningiomas and glioblastomas from a genomic locus that evolved by duplication of the NOS2A gene followed by internal DNA inversion. | 18820242 | LncRNADisease Lnc2Cancer |