Related LncRNAs |
ID |
lncRNA Name |
Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
EL0556 |
H19 |
meningioma |
N/A |
N/A |
N/A |
epigenetics |
An examination of meningiomas (World Health Organization grades I-III) demonstrated more robustly that the imprinting status of H19 is perturbed with LOI in a significant number of these tumors. |
20380817 |
LncRNADisease
|
EL0556 |
H19 |
meningioma |
N/A |
N/A |
N/A |
regulation |
Epigenetic deregulation of lncRNAs genes is associated with disease |
23791884 |
LncRNADisease
|
EL0556 |
H19 |
meningioma |
qPCR etc. |
meningioma tissue |
differential expression |
N/A |
In total, 24 meningiomas of WHO grade I, II and III were analysed. 15 meningiomas (63%) were informative for the ApaI polymorphism in the IGF2 gene. Monoallelic expression (MAE) for IGF2 was found in 11 out of 15 tumours (73%) which is in contrast to the lack of imprinting status of IGF2 in leptomeninges. Ten cases (42%) were heterozygous for the H19 gene and biallelic expression was found in 3 out of 10 meningiomas (30%). These results indicate that modulation of the imprinting status of IGF2 and H19 may play an important role for the development of meningiomas. |
10738131 |
Lnc2Cancer
|
EL0861 |
MEG3 |
meningioma |
N/A |
N/A |
N/A |
regulation |
MEG3: a novel long noncoding potentially tumour-suppressing RNA in meningiomas. |
23307326 |
LncRNADisease
|
EL0861 |
MEG3 |
meningioma |
qPCR, Luciferase reporter assay, ISH etc. |
meningioma tissue |
down-regulated |
epigenetics |
Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. |
20179190 |
LncRNADisease Lnc2Cancer
|
EL0986 |
NOS2 |
meningioma |
qPCR etc. |
meningioma tissue |
up-regulated |
expression |
anti-NOS2A is a lncRNA that is expressed in meningiomas and glioblastomas from a genomic locus that evolved by duplication of the NOS2A gene followed by internal DNA inversion. |
18820242 |
LncRNADisease Lnc2Cancer
|
|