Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0082 APTR glioblastoma qPCR, Northern blot, Luciferase reporter assays, knockdown etc. primary glioblastoma tissue, cell lines (A172, HCT116) up-regulated N/A We identified a novel lncRNA, APTR, that acts in trans to repress the CDKN1A/p21 promoter independent of p53 to promote cell proliferation. 24748121 Lnc2Cancer
EL0556 H19 glioblastoma N/A N/A N/A expression Another study performed in CD133+ and CD133- glioblastoma derived primary cell lines revealed levels of H19 expression that were relatively high and low, respectively. 20380817 LncRNADisease
EL0556 H19 glioblastoma qPCR, Neurosphere Formation assay etc. glioblastoma tissue, cell lines (U87, U373) up-regulated expression H19 is significantly overexpressed in glioblastoma tissues, and the level of expression was associated with patient survival. In the subsequent investigations, the authors found that overexpression of H19 promotes glioblastoma cell invasion and angiogenesis in vitro. Interestingly, H19 was also significantly overexpressed in CD133+ glioblastoma cells, and overexpression of H19 was associated with increased neurosphere formation of glioblastoma cells. 26274999 Lnc2Cancer
EL0853 MALAT1 glioblastoma N/A N/A N/A N/A Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse WIF1 re-expression in glioblastoma inhibits migration through attenuation of non-canonical WNT signaling by downregulating the lncRNA MALAT1. 25772239 LncRNADisease
EL0986 NOS2 glioblastoma qPCR etc. glioblastoma tissue up-regulated expression anti-NOS2A is a lncRNA that is expressed in meningiomas and glioblastomas from a genomic locus that evolved by duplication of the NOS2A gene followed by internal DNA inversion. 18820242 LncRNADisease Lnc2Cancer
EL1459 XIST glioblastoma qPCR, Luciferase reporter assay, RIP etc. glioblastoma tissue up-regulated expression Our results proved that XIST expression was up-regulated in glioma tissues and GSCs. Functionally, knockdown of XIST exerted tumor-suppressive functions by reducing cell proliferation, migration and invasion as well as inducing apoptosis. 25578780 Lnc2Cancer