Related LncRNAs |
ID |
lncRNA Name |
Disease |
Method |
Sample |
Expression pattern |
Dysfunction type |
Description |
PMID |
Source |
EL0272 |
CASC2 |
endometrial cancer |
N/A |
N/A |
N/A |
mutation |
CASC2, in a region of common allelic loss at chromosome 10q26 is a novel candidate gene in human endometrial cancer. |
15024726 |
LncRNADisease
|
EL0456 |
TDGF1P1 |
endometrial cancer |
microarray, qPCR etc. |
endometrial carcinoma tissue |
up-regulated |
expression |
The results showed that seven of these lncRNAs were in accordance with microarray data, including three up-regulated lncRNAs (uc003xut., uc021re1.1, ENST00000445734) and four down-regulated ones (uc002nbr.3, ENST00000502941, ENST00000448093, ENST00000503710). |
26131074 |
Lnc2Cancer
|
EL0457 |
ZNRD1ASP |
endometrial cancer |
microarray, qPCR etc. |
endometrial carcinoma tissue |
down-regulated |
expression |
The results showed that seven of these lncRNAs were in accordance with microarray data, including three up-regulated lncRNAs (uc003xut., uc021re1.1, ENST00000445734) and four down-regulated ones (uc002nbr.3, ENST00000502941, ENST00000448093, ENST00000503710). |
26131074 |
Lnc2Cancer
|
EL0465 |
HAND2-AS1 |
endometrial cancer |
microarray, qPCR etc. |
endometrial carcinoma tissue |
down-regulated |
expression |
The results showed that seven of these lncRNAs were in accordance with microarray data, including three up-regulated lncRNAs (uc003xut., uc021re1.1, ENST00000445734) and four down-regulated ones (uc002nbr.3, ENST00000502941, ENST00000448093, ENST00000503710). |
26131074 |
Lnc2Cancer
|
EL0466 |
AC012312.1 |
endometrial cancer |
microarray, qPCR etc. |
endometrial carcinoma tissue |
down-regulated |
expression |
The results showed that seven of these lncRNAs were in accordance with microarray data, including three up-regulated lncRNAs (uc003xut., uc021re1.1, ENST00000445734) and four down-regulated ones (uc002nbr.3, ENST00000502941, ENST00000448093, ENST00000503710). |
26131074 |
Lnc2Cancer
|
EL0526 |
GAS5 |
endometrial cancer |
qPCR, Western blot, knockdown, Luciferase reporter assay, Flow cytometry assay etc. |
endometrial cancer tissue, cell lines (HHUA, JEC) |
down-regulated |
interaction |
We identified that GAS5 was down-regulated in endometrial cancer cells and stimulated the apoptosis of endometrial cancer cells. In summary, we demonstrate that GAS5 acts as an tumor suppressor lncRNA in endometrial cancer. Through inhibiting the expression of miR-103, GAS5 significantly enhanced the expression of PTEN to promote cancer cell apoptosis, and, thus, could be an important mediator in the pathogenesis of endometrial cancer. |
26511107 |
Lnc2Cancer
|
EL0578 |
HOTAIR |
endometrial cancer |
qPCR etc. |
endometrial carcinoma tissue |
up-regulated |
expression |
The long non-coding RNA HOTAIR is upregulated in endometrial carcinoma and correlates with poor prognosis. |
24285342 |
LncRNADisease Lnc2Cancer
|
EL0578 |
HOTAIR |
endometrial cancer |
qPCR, knockdown etc. |
endometrioid carcinoma tissues, cell lines (HEC-1A, HEC-1B, Ishikawa, RL-952) |
up-regulated |
regulation |
Lentivirus-Mediated?RNA?Interference Targeting the?Long?Noncoding?RNA?HOTAIR Inhibits Proliferation and Invasion of Endometrial Carcinoma Cells In Vitro and In Vivo. |
24758900 |
LncRNADisease Lnc2Cancer
|
EL0578 |
HOTAIR |
endometrial cancer |
RT-qPCR |
156 consecutive, stage I-IV EC patients |
N/A |
N/A |
high HOTAIR expression correlated with shorter overall survival |
26868332 |
|
EL0637 |
LA16c-313D11.11 |
endometrial cancer |
N/A |
endometrial cancer (EC) |
down-regulated |
interaction |
Two novel genes RP11-395G23.3 and LA16c-313D11.11 associated with endometrial cancer were identified and proved to be non-coding RNAs. |
26807189 |
|
EL1140 |
AC027031.2 |
endometrial cancer |
N/A |
endometrial cancer (EC) |
down-regulated |
expression |
Two novel genes RP11-395G23.3 and LA16c-313D11.11 associated with endometrial cancer were identified and proved to be non-coding RNAs. |
26807189 |
|
EL1223 |
SNHG12 |
endometrial cancer |
microarray, qPCR etc. |
endometrial carcinoma tissue |
up-regulated |
expression |
ASLNC04080 was the most significantly upregulated lncRNA in microarray data, highly expressed in 22 out of 24 endometrial carcinoma tissues and HEC-1-B cell line. Moreover, the ASLNC04080 lncRNA expression was correlated with 19 coding genes, and may contribute to endometrial carcinoma genesis and progression by co-regulating with coding gene. Expression inhibition of lncRNA ASLNC04080 in HEC-1-B cells caused repression of cell proliferation, increased cell apoptosis, and G1 phase arrest. |
25695231 |
Lnc2Cancer
|
EL1419 |
uc002nbr.3 |
endometrial cancer |
microarray, qPCR etc. |
endometrial carcinoma tissue |
down-regulated |
expression |
The results showed that seven of these lncRNAs were in accordance with microarray data, including three up-regulated lncRNAs (uc003xut., uc021re1.1, ENST00000445734) and four down-regulated ones (uc002nbr.3, ENST00000502941, ENST00000448093, ENST00000503710). |
26131074 |
Lnc2Cancer
|
EL1425 |
AC091173.1 |
endometrial cancer |
microarray, qPCR etc. |
endometrial carcinoma tissue |
up-regulated |
expression |
The results showed that seven of these lncRNAs were in accordance with microarray data, including three up-regulated lncRNAs (uc003xut., uc021re1.1, ENST00000445734) and four down-regulated ones (uc002nbr.3, ENST00000502941, ENST00000448093, ENST00000503710). |
26131074 |
Lnc2Cancer
|
EL1429 |
uc021re1.1 |
endometrial cancer |
microarray, qPCR etc. |
endometrial carcinoma tissue |
up-regulated |
expression |
The results showed that seven of these lncRNAs were in accordance with microarray data, including three up-regulated lncRNAs (uc003xut., uc021re1.1, ENST00000445734) and four down-regulated ones (uc002nbr.3, ENST00000502941, ENST00000448093, ENST00000503710). |
26131074 |
Lnc2Cancer
|
|