Related LncRNAs
ID	lncRNA Name	Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
EL0242	BGLT3	chronic myeloid leukemia	microarray, qPCR, Western blot etc.	cell lines (K562)	up-regulated	N/A	We observed that lncRNA-BGL3 was highly induced in response to disruption of Bcr-Abl expression or by inhibiting Bcr-Abl kinase activity in K562 cells and leukemic cells derived from CML patients. Ectopic expression of lncRNA-BGL3 sensitized leukemic cells to undergo apoptosis and inhibited Bcr-Abl-induced tumorigenesis.	24837367	Lnc2Cancer
EL0556	H19	chronic myeloid leukemia	qPCR, Western blot etc.	cell lines (K562)	up-regulated	N/A	We observed that H19 was highly expressed in Bcr-Abl-expressing primary CML cells derived from 4 patients, and imatinib treatment greatly decreased the expression of H19 in these cells but not in normal control cells. Loss of either Bcr-Abl expression or Abl kinase activity caused decrease of c-Myc levels with simultaneously reduced levels of H19. Furthermore, we demonstrated that depletion of c-Myc alone in K562 cells significantly decreased the level of H19, suggesting that H19 is expressed in a c-Myc dependent manner in K562 leukemic cells.	24685695	Lnc2Cancer
EL0861	MEG3	chronic myeloid leukemia	qPCR, ISH etc.	blood	down-regulated	expression	MEG3 expression is lost.	14602737	LncRNADisease Lnc2Cancer