Related LncRNAs
ID lncRNA Name Disease Method Sample Expression pattern Dysfunction type Description PMID Source
EL0296 CHRF cardiac hypertrophy N/A N/A N/A regulation The Long Noncoding RNA CHRF Regulates Cardiac Hypertrophy by Targeting miR-489. 24557880 LncRNADisease
EL0556 H19 cardiac hypertrophy N/A normal and diseased hearts up-regulated N/A overexpression of H19 reduced cell size both at baseline and in response to PE; knockdown of H19 induced cardiomyocyte hypertroph 27084844
EL1120 RN7SK cardiac hypertrophy N/A N/A N/A Interaction Together with the HEXIM proteins, 7SK RNA associates with and sequesters a fraction of cellular P-TEFb into a catalytically inactive complex. Active and inactive forms of P-TEFb are kept in a functional and dynamic equilibrium tightly linked to the transcriptional requirement of the cell. Importantly, cardiac hypertrophy and development of various types of human malignancies have been associated with increased P-TEFb activity, consequence of a disruption of this regulatory equilibrium. 22377309 LncRNADisease