EL0578 |
HOTAIR |
bladder transitional cell carcinoma |
quantitative real-time PCR, MTT assay, Dual-color flow cytometric method |
bladder transitional cell carcinoma (TCC) tissues and cell lines |
up-regulated |
expression |
HOTAIR over-expression promoted cell proliferation and inhibited chemosensitivity to doxorubicin and cell apoptosis induced by doxorubicin; silence of HOTAIR showed opposite regulative effects. lncRNA HOTAIR was an independent prognostic biomarker of overall survival in TCC patients and could regulate chemosensitivity to doxorubicin of human TCC cells. |
26781446 |
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