Related LncRNAs
ID	lncRNA Name	Disease	Method	Sample	Expression pattern	Dysfunction type	Description	PMID	Source
EL0556	H19	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	epigenetics	Mosaicism for 11p15 UPD and hypermethylation of the H19 gene in blood cells were associated with an increased risk of tumour.	11436121	LncRNADisease
EL0556	H19	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	epigenetics	Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects.	11813134	LncRNADisease
EL0556	H19	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	mutation	Microdeletions in the human H19 DMR result in loss of IGF2 imprinting and Beckwith-Wiedemann syndrome.	15314640	LncRNADisease
EL0556	H19	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	locus	The H19 locus acts in vivo as a tumor suppressor.	18719115	LncRNADisease
EL0556	H19	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	epigenetics	Allelic methylation of H19 and IGF2 in the Beckwith-Wiedemann syndrome.	7987305	LncRNADisease
EL0628	KCNQ1OT1	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	locus	KvDMR1 and/or its associated antisense RNA (KvLQT1-AS) represents an additional imprinting control element or center in the human 11p15.5 and mouse distal 7 imprinted domains.	10393948	LncRNADisease
EL0628	KCNQ1OT1	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	locus	The LIT1 CpG island can act as a negative regulator in cis for coordinate imprinting at the centromeric domain, thereby suggesting a role for the LIT1 locus in a BWS pathway leading to functional inactivation of p57(KIP2).	10958646	LncRNADisease
EL0628	KCNQ1OT1	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	epigenetics	The 5'end of the KCNQ1OT1 gene is hypomethylated in the Beckwith-Wiedemann syndrome.	12136243	LncRNADisease
EL0628	KCNQ1OT1	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	N/A	In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN1OT gene.	12746837	LncRNADisease
EL0628	KCNQ1OT1	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	locus	In the human and mouse BWS imprinting regions, two major elements for regulation of imprinted gene expression have been identified athe imprinting centers IC1 and IC2.IC2 appears to be the promoter of the paternally expressed probably noncoding transcript.	15590939	LncRNADisease
EL0628	KCNQ1OT1	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	N/A	LIT1 (KCNQ1OT1) may play a role in Beckwith-Wiedemann syndrome.	15888726	LncRNADisease
EL0628	KCNQ1OT1	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	epigenetics	In Beckwith-Wiedemann syndrome (BWS), approximately 50% of patients show loss of DNA methylation accompanied by loss of histone H3 Lys9 dimethylation on maternal KCNQ1OT-DMR, namely an imprinting disruption, leading to diminished expression of CDKN1C.	16575194	LncRNADisease
EL0628	KCNQ1OT1	Beckwith-Wiedemann syndrome	N/A	N/A	N/A	regulation	Epigenetic deregulation of lncRNAs genes is associated with disease	23791884	LncRNADisease